{"product_id":"slu-pp-915-500mg","title":"SLU-PP-915 500mg","description":"\u003cp\u003e\u003cstrong\u003ePan-ERR Agonist for Metabolic Research\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eSLU-PP-915 is a synthetic small molecule that activates estrogen-related receptors ERRα, ERRβ, and ERRγ. These nuclear receptors regulate pathways involved in mitochondrial function and cellular energy metabolism. SLU-PP-915 is a boronic-acid-containing thiophene carboxamide studied in cell and animal models.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Background\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThe 2023 discovery study identified SLU-PP-915 as compound 10s and reported activation of ERR-dependent gene expression. A 2024 study investigated ERR-mediated regulation of TFEB and autophagy using SLU-PP-915 in cellular models. A subsequent study, published in the January 2026 issue of \u003cem\u003eThe Journal of Pharmacology and Experimental Therapeutics\u003c\/em\u003e, characterized oral activity and enhanced aerobic exercise capacity in mice.\u003c\/p\u003e\u003cp\u003eThese preclinical findings support use as a research tool for ERR signaling, mitochondrial energetics, and metabolic biology. They do not establish safety, efficacy, or exercise-performance benefits in humans.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eProduct Details\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eAmount: 500 mg\u003cbr\u003eFormat: Powder\u003cbr\u003eCAS: 2285432-92-8\u003cbr\u003eMolecular formula: C17H13BFNO3S\u003cbr\u003eMolecular weight: 341.16 g\/mol\u003cbr\u003eCategory: Metabolic\u003cbr\u003eProduct type: Small Molecule\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Publications\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eHampton CS et al. \u003ca href=\"https:\/\/doi.org\/10.1016\/j.ejmech.2023.115582\"\u003eDevelopment and pharmacological evaluation of a new chemical series of potent pan-ERR agonists, identification of SLU-PP-915\u003c\/a\u003e. \u003cem\u003eEuropean Journal of Medicinal Chemistry\u003c\/em\u003e. 2023;258:115582.\u003c\/li\u003e\n\u003cli\u003eLosby M et al. \u003ca href=\"https:\/\/doi.org\/10.1124\/molpharm.124.000889\"\u003eThe Estrogen Receptor-Related Orphan Receptors Regulate Autophagy through TFEB\u003c\/a\u003e. \u003cem\u003eMolecular Pharmacology\u003c\/em\u003e. 2024;106(4):164–172.\u003c\/li\u003e\n\u003cli\u003eBillon C et al. \u003ca href=\"https:\/\/doi.org\/10.1016\/j.jpet.2025.103787\"\u003eAn orally active estrogen receptor-related receptor agonist, SLU-PP-915, enhances aerobic exercise capacity\u003c\/a\u003e. \u003cem\u003eThe Journal of Pharmacology and Experimental Therapeutics\u003c\/em\u003e. 2026;393(1):103787.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eFor laboratory research use only. Not for human consumption or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/p\u003e","brand":"Molecule Frontier","offers":[{"title":"Default Title","offer_id":45954623012917,"sku":null,"price":99.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0707\/9929\/4517\/files\/slu-pp-915-molecule-white-black_f1708eb8-1144-40f5-b573-b6d56489d6bf.png?v=1790045219","url":"https:\/\/moleculefrontier.myshopify.com\/products\/slu-pp-915-500mg","provider":"MoleculeFrontier","version":"1.0","type":"link"}